On 29 May 2025, Japan’s Ministry of Environment (MoE), launched a public consultation to collect toxicity data on chemical substances regulated under the Chemical Substances Control Law (CSCL). The MoE has requested this data to further accelerate and optimize the risk assessment of Priority Assessment Chemicals (PACs) and general chemicals under the CSCL.  

Background 

The MoE periodically reviews the toxicity information of chemicals to help protect human health and the environment. It also revises the classification accordingly and makes this information publicly available through the Ministry’s portal. 

Chemicals covered under the consultation  

The consultation covers two classes of chemicals under the CSCL: 

• PACs: 53 entries  

• General Chemicals: 81 entries 

Information to be submitted 

The MoE requests companies to submit toxicity information for the following endpoints: 

• Acute or chronic toxicity to algae 

• Acute or chronic toxicity to crustaceans 

• Acute or chronic toxicity to fish 

The Ministry has also shared guidance on assessment methods and the preparation of documents for submission, which is available in detail through the consultation notice. 

Consultation Period 

Stakeholders are invited to submit the required toxicity information to the MoE by 31 July 2025.